The profound impact of hormonal imbalances on patient well-being

Menopause and andropause mark a critical transition in midlife, often involving significant hormonal changes that impact metabolism, cardiovascular function, mood, sleep and cognitive health. For many, standard hormone replacement therapy (HRT) offers relief—but is not suitable for all patients. Fixed-dose formulations don’t always account for individual clinical needs, leaving some patients with inadequate symptoms or adverse effects. Some may also have difficulty swallowing pills or be allergic to excipients and cannot tolerate standard medications. 

But what if there was a way to customise hormone therapies to meet individual patient needs? 

Compounded hormone therapies allow for precision in treatment, addressing a patient’s unmet clinical need. Whether it’s a patient struggling with side effects from oral tablets or someone needing an alternative dosage form, compounded medications provide flexible solutions.

The choice of specialised bases plays a key role in how these therapies are delivered and absorbed. Personalised medications can be customised to:

• Offer a range of dosage forms – Patients who cannot tolerate oral tablets may benefit from alternatives such as creams, gels or lozenges.
• Provide both local and systemic absorption – We use vaginal bases that enable hormones to be absorbed locally to treat genitourinary symptoms while also entering systemic circulation for broader symptom relief.
• Contain different hormone combinations and strengths – Unlike standard therapies, compounded medications allow for precise dosing and tailored hormone ratios to better match individual clinical needs.

Our recent report provides comprehensive insight into the role of compounded HRT and TRT, and how specialised bases enable alternative formulations for patients whose medical needs are not met by standard medications.

Download our latest report to learn more.